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John S. O'Meara
John S. O'Meara
Undergraduate Researcher
Allen School of Computer Science
University of Washington
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John S. O'Meara

Hello! I'm an undergraduate student at UW's Allen School of Computer Science in Seattle, WA.

Through my work, I hope to answer two questions:

  • How can machine learning help us understand how genetic variation shapes human biology?

  • How do we ensure that AI benefits humanity?

I think these are two of the most pressing questions of the century, and I hope to spend a good part of my life working on them.

Right now, I'm particularly interested in applying AI to genomics. One long-term goal of mine is to generate high-quality embedding representations for every possible SNP in the human genome.

Previously, I was a researcher at the Makeability Lab, where I led the RampNet project under the guidance of Prof. Jon Froehlich.

Feel free to email me about anything at hi@johnomeara.com. If you're unsure whether to reach out, please err on the side of doing so!

Blog Posts

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A vector illustration of space and the cosmos.

Where is the AI?

If intelligent alien civilizations and recursively self-improving AI exist, why hasn't superintelligent AI conquered the universe?

  • Essay
  • AI
Read post →
Scaling Sequence-to-Omics Models

Scaling Sequence-to-Omics Models

Exploratory experiments on dataset breadth, parameter count, track diversity, and transformer depth in sequence-to-omics models.

  • Genomics
  • AI
Read post →Code ↗Runs data ↗

Projects

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OpenMPRA database interface with its MPRA sequence illustration and study browser

OpenMPRA

A database of MPRA studies, experiment metadata, and processed data.

  • Genomics
  • AI
About the project →Website ↗Code ↗
Street View imagery showing RampNet curb ramp annotations

RampNet

Scaling curb ramp detection with open government data and street-level imagery.

  • Computer vision
  • Accessibility
  • AI
About the project →Website ↗Code ↗Read the paper ↗Dataset ↗
The banner image for the extracurriculars.org website.

Extracurriculars.org

Extracurriculars.org was a project I led that made niche, high-ROI extracurricular activities more accessible to the everyday student.

About the project →Website ↗
Picture of me (John O'Meara), Berkan, Aditya, and Ian after our HackPNW victory.

SATShark (1st Place at HackPNW Spring 2024)

Our competitive SAT studying game, SATShark, secured a 1st place victory against 140 other competitors at the 2024 HackPNW Spring hackathon.

About the project →Code ↗Demo Video ↗
See all projects →

Featured Publications

First page of the BikeButler paper

CHI · 2026

BikeButler: A Personalized, Context-sensitive Bike Routing Tool using Open Data and VLM-based Analyses of Street View Imagery

Jared Hwang, John O’Meara, Zeyu Wang, Jasmine Zhang, and Jon E. Froehlich

  • AI
  • HCI
  • Urban computing
Publication ↗PDF ↗Website ↗Code ↗
First page of the RampNet paper

ICCV CV4A11y Workshop · 2025

RampNet: A Two-Stage Pipeline for Bootstrapping Curb Ramp Detection in Streetscape Images from Open Government Metadata

John O’Meara, Jared Hwang, Zeyu Wang, Mikey Saugstad, and Jon E. Froehlich

  • AI
  • Computer vision
  • Accessibility
Publication ↗PDF ↗Code ↗Dataset ↗Project: RampNet →